Introduction #
Patient-centered care (PCC) has emerged as a fundamental pillar of modern healthcare delivery and represents a paradigm shift from traditional disease-focused, paternalistic models toward approaches that integrate patients’ perspectives, needs, and experiences into every phase of medical consultation, treatment, and follow-up [1]. As healthcare systems worldwide evolve to address growing complexity, fragmentation, and persistent health disparities, PCC has been recognized as essential not only for improving individual patient outcomes but also for transforming healthcare delivery at the systems level [2,3].
Health Systems Science (HSS), established as the third pillar of medical education alongside basic and clinical sciences, provides a unified framework for contextualizing healthcare delivery and caring for patients and populations within adaptive health systems [4]. Patient-centered care sits at the intersection of HSS domains, connecting quality improvement, population health, care coordination, and value-based care with the fundamental principle that healthcare must honor and respond to individual patient preferences, needs, values, and goals [5].
Defining Patient-Centered Care #
The Institute of Medicine (IOM) defines patient-centered care as “providing care that is respectful of and responsive to individual patient preferences, needs, and values, and ensuring that patient values guide all clinical decisions” [6]. This definition, first formally championed by the Picker Institute in 1988 and later popularized by the IOM’s seminal 2001 report “Crossing the Quality Chasm,” established patient-centeredness as one of six crucial domains of healthcare quality, alongside safety, effectiveness, timeliness, efficiency, and equity [7,8].
The IOM endorsed six dimensions of patient-centered care, originally established by the Picker Institute, which stipulate that care must be: (1) respectful to patients’ values, preferences, and expressed needs; (2) coordinated and integrated; (3) provide information, communication, and education; (4) ensure physical comfort; (5) provide emotional support to relieve fear and anxiety; and (6) involve family and friends [9,10]. These dimensions provide a comprehensive framework for both evaluating and implementing patient-centered care across diverse healthcare settings.
Despite widespread agreement on its importance, consensus on what constitutes PCC remains elusive, with multiple definitions and conceptual models existing in the literature [11,12]. Most providers, policymakers, and researchers agree that PCC represents a shift from traditional, provider-driven and disease-focused approaches toward one that fully integrates the patient’s perceptions, needs, and experiences into healthcare delivery [13]. Mead and Bower’s influential literature review describes PCC as encompassing five conceptual dimensions: the biopsychosocial perspective, patient-as-person, sharing power and responsibility, therapeutic alliance, and doctor-as-person [14].
Core Components of Patient-Centered Care #
Shared Decision-Making
Shared decision-making (SDM) represents the pinnacle of patient-centered care, embodying an interactive, collaborative process where physicians focus on the best scientific evidence while patients contribute their goals, preferences, and values to make healthcare decisions [15,16]. Barry and Edgman-Levitan articulate that the most important attribute of patient-centered care is the active engagement of patients when fateful healthcare decisions must be made, particularly at crossroads where diverging medical options have different and important consequences [17].
Contemporary models of SDM extend beyond traditional decision-making about predetermined treatment options to encompass a broader collaborative approach where patients and clinicians work together to determine the nature of the problematic situation, consider insights that only the patient can share about their biology and biography, and develop sensible care plans based on relevant evidence and patient priorities [18,19]. Research demonstrates that SDM improves patient satisfaction, increases patient knowledge, reduces decisional conflict, and enhances communication between patients and clinicians [20,21]. Systematic reviews indicate that patient decision aids can reduce the prevalence of invasive procedures when patients are fully informed about risks and benefits of various options, while improving health outcomes such as treatment adherence and clinical measures like quality of life [22,23].
Patient-Centered Communication
Effective patient-centered communication serves as the foundation for achieving patient-centered care and represents a critical clinical competence that affects healthcare quality, patient satisfaction, and health outcomes [24,25]. Patient-centered communication has been associated with improved health outcomes including better physiologic measures such as blood pressure and blood glucose levels, improved health status, reduced depression and anxiety, and enhanced functional status with less patient distress [26,27].
A consensus has emerged around six core functions for medical encounters that support patient-centered communication: (1) fostering the relationship, (2) gathering information, (3) providing information, (4) making decisions, (5) responding to emotions, and (6) enabling disease- and treatment-related behavior or self-management [28]. Communication should simultaneously employ a patient-centered approach and interpersonal interaction to promote patient satisfaction, while avoiding overly directive communication patterns that can have negative consequences [29].
Research in psychotherapy contexts demonstrates that patient-centered communication accounts for approximately 30 percent of the variance in symptom improvement and leads to improvements in overall quality of life measures, with patients experiencing higher levels of patient-centered communication reporting significant improvements in functional status and subjective well-being [30]. Furthermore, studies have shown that patient-centered communication increases patient engagement, with effective communication strategies being essential for enabling patients to engage actively in their care [31,32].
Cultural Competence and Health Equity
Cultural competence, defined as the ability of healthcare providers to effectively deliver services that meet the social, cultural, and linguistic needs of patients, intersects significantly with patient-centered care in addressing health disparities and improving healthcare quality [33,34]. The National Standards for Culturally and Linguistically Appropriate Services (CLAS) provide a comprehensive framework for implementing culturally competent care that respects diversity and cultural factors affecting health, including language, communication styles, beliefs, attitudes, and behaviors [35].
Patient-centeredness has theoretical potential to reduce racial and ethnic disparities in healthcare because it addresses some hypothesized mechanisms by which patient race and ethnicity impact healthcare providers, including biases in decision-making and unequal power dynamics between patients and providers [36,37]. Research indicates that bias, stereotyping, prejudice, and clinical uncertainty on the part of healthcare providers contribute to racial and ethnic disparities, with persons in minority groups receiving lower-quality healthcare even when insurance status and ability to pay are equivalent [38,39].
An evolving concept of “cultural humility” emphasizes identifying one’s own implicit biases, cultivating self-understanding and interpersonal sensitivity, and appreciating the multifaceted components of each individual including culture, gender, sexual identity, race, ethnicity, religion, and lifestyle [40]. This concept, combined with cultural competence in what some term “competemility,” requires both process (cultural humility) and product (cultural competence) to interact effectively with culturally diverse patients [41].
Patient Engagement and Activation #
Patient engagement represents a broader concept that combines patient activation with interventions designed to increase activation and promote positive patient behaviors [42]. Patient activation refers to a patient’s knowledge, skills, ability, and willingness to manage his or her own health and care [43]. Research consistently demonstrates that patients who are more activated experience better health outcomes and incur lower costs compared to less activated patients [44,45].
The Patient-Centered Outcomes Research Institute (PCORI) has been instrumental in advancing patient engagement in research, requiring investigators to engage patients and other healthcare stakeholders throughout the research process from topic selection through design, conduct, and dissemination of results [46,47]. Analysis of PCORI-funded projects reveals that patient engagement provides valuable contributions to research feasibility, acceptability, rigor, and relevance, with engaged patients and stakeholders contributing to study design, outcome selection, intervention tailoring, and participant enrollment [48].
A scoping review of patient engagement impact identified four key outcome categories: (1) health outcomes and effectiveness, including improved quality of care and patient satisfaction; (2) patient compliance with improved adherence to treatment processes; (3) self-efficacy with increased patient responsibility and motivation for health management; and (4) return on investment considerations including cost-effectiveness [49]. Evidence suggests that engaging patients helps reshape care and treatment in ways that fit their needs and preferences, ultimately resulting in improved outcomes [50].
Health Systems Science Integration #
The integration of patient-centered care within Health Systems Science represents a critical evolution in medical education and healthcare delivery [51,52]. HSS emerged to address competency gaps in healthcare professionals who must practice within increasingly complex, adaptive health systems characterized by fragmentation, growing health inequities, and multiple stakeholders [53]. The shift toward patient-centered care requires competencies including demonstrating cultural humility, taking holistic and systems-based approaches, and practicing effective communication and coordination [54].
Medical education initiatives incorporating HSS aim to develop “systems citizens”—physicians who understand they are part of complex adaptive systems and who strive to improve patient care and population health [55,56]. Value-added clinical systems learning roles in medical education have demonstrated that experiential opportunities focused on patient-centered care can enhance students’ understanding of patients’ perspectives on healthcare, barriers and social determinants of health, healthcare systems and delivery, interprofessional collaboration, and communication approaches [57,58].
Graduate medical education programs increasingly recognize that core domains encompassed by HSS—including patient safety, healthcare quality, care transitions, well-being, and professionalism—directly align with competencies needed to deliver patient-centered care [59]. The development of HSS distinction tracks and curricula aims to create physicians equipped with tools needed to achieve the quintuple aim of improved patient experience, better health outcomes, reduced costs, enhanced provider satisfaction, and health equity [60].
Implementation and Organizational Factors #
Successfully implementing patient-centered care requires organizational focus on leadership values, human resources policies that recruit and retain staff with aptitudes for service and empathy, and continuous measurement of patient experience using well-designed surveys and qualitative methods [61]. Healthcare organizations must actively understand what patients value through methods such as focus groups, interviews, and partnership with patients and families in co-designing care, educational materials, and communication resources [62].
Research on high-performing healthcare organizations reveals that tensions may arise when attempting to deliver both evidence-based practice and patient-centered care, but organizations that excel in both domains share unique characteristics including strong communication cultures, institutional prioritization of both domains in performance feedback, and dedicated cross-department organizing bodies for implementation work [63,64]. Best practices for facilitating patient-centered care and care coordination include institutional values surrounding PCC, optimization of information technology infrastructure to enhance performance and communication, appropriate pay structures and employee incentives, and dedicated implementation teams [65].
Major barriers to delivering patient-centered care identified in peer-reviewed literature include: (1) challenges in understanding patient context and collecting necessary information, (2) difficulties building trust and mutual respect between patients and providers, (3) misalignment of incentives with patient-centered care goals, and (4) lack of cultural change within medical practice to support PCC delivery [66]. Addressing these barriers requires multi-level interventions spanning individual provider training, care team development, organizational transformation, and health system redesign.
Outcomes and Evidence Base #
The evidence base supporting patient-centered care continues to grow, demonstrating associations with multiple positive outcomes across diverse clinical settings and patient populations [67]. Research indicates that PCC improves healthcare outcomes for chronic diseases including depression and anxiety disorders, cardiovascular disease, diabetes, and substance use disorders [68,69]. By improving health outcomes for inpatients and reducing physician-induced demand, PCC benefits both patients and health insurance systems [70].
Studies examining patient-centered care in hospital settings reveal that patients’ experiences of PCC are associated with greater satisfaction, reduced symptom burden, enhanced trust in the healthcare system, and perceptions of excellent and trustworthy care [71]. When care continuity, clear accountability, and caring attitudes are achieved across the care continuum, patients and caregivers feel supported rather than abandoned by the healthcare system [72].
The relationship between patient-centered care and health outcomes appears mediated through multiple mechanisms including improved patient engagement, enhanced therapeutic alliance, better treatment adherence, and more effective management of uncertainty [73,74]. Furthermore, patient-centered communication has been shown to increase patient satisfaction across multiple dimensions including relationships with physicians and other healthcare professionals, with stronger relationships when patients perceive higher levels of patient-centered behaviors [75].
Challenges and Future Directions #
Despite substantial progress in conceptualizing and promoting patient-centered care, significant challenges remain in translating principles into consistent practice [76]. Healthcare employees’ conceptualizations of PCC vary widely, with understanding ranging from focusing on patient perspectives and needs to more operational definitions involving specific processes and behaviors [77]. This variability in understanding can impede systematic implementation and evaluation of patient-centered care initiatives.
Future research must address several critical gaps including better understanding of how to measure patient-centered care comprehensively across all six IOM dimensions, developing validated patient-reported measures that capture the full spectrum of patient-centeredness, and identifying strategies for sustaining PCC implementation in resource-constrained environments [78,79]. Additionally, research is needed on the long-term impact of medical education initiatives incorporating patient-centered care principles on practicing physicians’ behaviors and patient outcomes [80].
The digital transformation of healthcare presents both opportunities and challenges for patient-centered care [81]. While technologies like patient portals, telemedicine, and electronic health records can enhance access and communication, they may also exacerbate disparities if not carefully designed with equity considerations, particularly for populations on the disadvantaged side of the digital divide [82]. Ensuring that technological innovations support rather than undermine patient-centered care will require thoughtful implementation with meaningful patient and community engagement.
Conclusion #
Patient-centered care represents a fundamental transformation in how healthcare is conceptualized and delivered, shifting from disease-focused, provider-driven models to approaches that honor patients as whole persons with unique values, preferences, needs, and goals. Within the framework of Health Systems Science, patient-centered care connects individual clinical encounters with broader systems-level concerns including quality improvement, population health, care coordination, and health equity. The growing evidence base demonstrates that patient-centered care improves patient satisfaction, health outcomes, and potentially healthcare costs, while presenting implementation challenges that require sustained attention to organizational culture, provider training, and system redesign. As healthcare continues to evolve toward greater complexity and integration, patient-centered care will remain essential for achieving high-quality, equitable healthcare that truly serves patients and populations.
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