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HMD MedDigest

Substance Over Noise

A physician-written newsletter on clinical medicine, evidence-based practice, and the science behind the headlines. No hot takes. No hedging. Just the evidence, well explained.

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Cardiology · Valvular Disease · Clinical Review

Aortic Stenosis: An Evidence-Based Approach

Narrowing of the aortic valve orifice that obstructs left ventricular outflow — from calcific degeneration to TAVR, a complete clinical review.

Apr 22, 2026·18 min read

Aortic Stenosis: An Evidence-Based Approach

The most common valvular heart disease in older adults — recognition, staging, and the modern intervention pathway from SAVR to TAVR.

HCR
HMD Clinical Review

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CardiologyValvular Disease+1

Mitral Regurgitation: An Evidence-Based Approach

Apr 22, 2026·16 min read

Mitral Regurgitation: An Evidence-Based Approach

Primary versus secondary MR, acute versus chronic — how the etiology dictates the therapy, and when to refer for repair.

HCR
HMD Clinical Review
CardiologyValvular Disease+1

Mitral Stenosis: An Evidence-Based Approach

Apr 22, 2026·15 min read

Mitral Stenosis: An Evidence-Based Approach

A valvular disease of the developing world and an aging-population problem in high-income settings — how to recognize and treat it.

HCR
HMD Clinical Review
CardiologyValvular Disease+1

Tricuspid Regurgitation: An Evidence-Based Approach

Apr 22, 2026·17 min read

Tricuspid Regurgitation: An Evidence-Based Approach

Functional versus primary TR, the emerging transcatheter options, and why chronic right-sided congestion is no longer a diagnosis of exclusion.

HCR
HMD Clinical Review
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